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DALYs: disability-adjusted life-years

ColRACI: colistin-resistant Acinetobacter spp.

CRACI: carbapenem-resistant Acinetobacter spp.

MDRACI: multidrug-resistant Acinetobacter spp.

VRE: vancomycin-resistant Enterococcus faecalis and Enterococcus faecium.

ColREC: colistin-resistant Escherichia coli.

CREC: carbapenem-resistant E coli.

3GCREC: third-generation cephalosporin-resistant E coli.

ColRKP: colistin-resistant Klebsiella pneumoniae.

CRKP: carbapenem-resistant K pneumoniae.

3GCRKP: third-generation cephalosporin-resistant K pneumoniae.

ColRPA: colistin-resistant Pseudomonas aeruginosa.

CRPA: carbapenem-resistant P aeruginosa.

MDRPA: multidrug-resistant P aeruginosa.

MRSA: meticillin-resistant Staphylococcus aureus.

PRSP: penicillin-resistant Streptococcus pneumoniae.

PMRSP: penicillin-resistant and macrolide-resistant S pneumoniae.

The methodology of Cassini et al. 2018 (1) was adapted to estimate the outcome of different parameters (infections, DALYs, deaths) in Switzerland. Regionally stratified data from the ANRESIS database was used as data source for bloodstream infections. As Cassini and colleagues did, we used the Burden of Communicable Disease in Europe toolkit for the estimation of the outputs based on 10’000 Monte Carlo simulations, without time discounting.

1: Cassini A et al. Impact of infectious diseases on population health using incidence-based disability-adjusted life years (DALYs): results from the Burden of Communicable Diseases in Europe study, European Union and European Economic Area countries, 2009 to 2013. Euro Surveill. 2018;23(16).

Select a region of interest or a unit of choice from the drop-down menus. Use the checkboxes to activate or deactivate time series and confidence intervals. When the mouse is moved over the graph a toolbar appears, which allows zooming, showing data on hover and downloading of the graph. A map of different ANRESIS regions can be found here.

ESCR-E.coli: Extended-spectrum cephalosporin-resistant Escherichia coli

ESCR-K.pneumoniae: Extended-spectrum cephalosporin resistant Klebsiella pneumoniae

FQR-E.coli: Fluoroquinolone-resistant Escherichia coli

MRSA: Methicillin-resistant Staphylococcus aureus

PNSP: Penicillin-non-susceptible Streptococcus pneumoniae

VRE: Vancomycin-resistant enterococci

95% CI: 95% confidence interval

For this analysis invasive isolates (blood and cerebrospinal fluid) tested against the corresponding antibiotic (category) were considered only. If multiple antibiotics within the same antibiotic category were tested, the most resistant result was selected. In case of multiple isolates, the first isolate per patient, microorganism and calendar year was included only. Results are reported as delivered by laboratories. Statistics may be influenced by the changing number of laboratories participating. Data are provided for surveillance purposes and are not intended to be used for therapeutic decisions solely.

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VRE: Vancomycin-resistant enterococci

year_1 and year_2: First (January-June) and second (July-December) six months of the year

From every patient the most invasive isolate which was sampled within one calendar year was included. Results are reported as delivered by laboratories. Results may be influenced by the changing number of laboratories participating.