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The clinical manifestations of infection with Candida species range from local mucous membrane infections to candidemia and widespread dissemination with multisystem organ failure. 

Candida albicans is still considered the main causative pathogen, a shift to non-albicans Candida species is observed globally. Candidemia is among the leading causes of hospital-acquired bloodstream infections, representing one of the most prevalent nosocomial  invasive fungal infections worldwide. Moreover, the emergence of drug-resistant Candida species are major concerns.

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